Weight management

Semaglutide

Wegovy · Weekly injection

What is semaglutide?

Semaglutide is a prescription medicine that acts on a hormone signal involved in appetite. Wegovy injection contains semaglutide and is FDA-approved for weight management in eligible patients, alongside a reduced-calorie diet and increased physical activity.

Explore a consultation Read important safety information

What the research studied

In the STEP 1 trial, researchers randomly assigned 1,961 adults without diabetes to semaglutide injections or a placebo. Participants had obesity, or overweight with at least one weight-related condition. Both groups received lifestyle support. The researchers compared changes in body weight after 68 weeks. The trial studied that injection in that population; it did not test every product called semaglutide.

STEP 1: Once-Weekly Semaglutide in Adults with Overweight or Obesity

What to discuss

Your health history and current medications
Whether a GLP-1 medication is appropriate
Nutrition, activity, and follow-up care

Important safety information

Wegovy carries a boxed warning about thyroid C-cell tumors observed in rodents; the risk in people is unknown. Do not use with a personal or family history of medullary thyroid carcinoma or MEN 2. Nausea, vomiting, diarrhea, and constipation are common. Serious risks include pancreatitis, gallbladder problems, dehydration-related kidney injury, and severe allergic reactions. Discuss pregnancy plans and all medications with a clinician. Do not combine with another semaglutide product or GLP-1 medicine. Read the full prescribing information and Medication Guide.

Wegovy prescribing information & Medication Guide

Questions about semaglutide

Is Wegovy a shot or a pill?

Wegovy comes as a weekly injection and as a daily tablet. This page covers the injection, which comes in a prefilled pen or syringe.

Did the Wegovy study test compounded semaglutide?

No. The STEP 1 trial compared Novo Nordisk’s semaglutide injection with a placebo. Its results apply to the formulation used in that trial.

How do I book a visit, and what does it cost?

The first weight management visit is $79. Choose Weight management on the consultation page to review the visit details. The clinical practice handles scheduling for your state. If your clinician prescribes semaglutide, the pharmacy quotes the medication separately. View consultation options