Weight management
Tirzepatide
Zepbound · Weekly injectionWhat is tirzepatide?
Tirzepatide is a prescription medicine that acts on two hormone signals involved in appetite, called GIP and GLP-1. Zepbound injection contains tirzepatide. It is FDA-approved for weight management in eligible adults, alongside a reduced-calorie diet and increased physical activity.
Explore a consultationRead important safety informationWhat the research studied
In SURMOUNT-1, researchers randomly assigned 2,539 adults without diabetes to tirzepatide injections or a placebo, alongside lifestyle changes. Participants had obesity, or overweight with at least one weight-related condition. They compared changes in body weight at 72 weeks. This trial did not compare tirzepatide with semaglutide.
SURMOUNT-1: Tirzepatide Once Weekly for the Treatment of ObesityWhat to discuss
- Your health history and current medications
- Treatment options and potential side effects
- A follow-up plan that supports long-term care
Important safety information
Zepbound carries a boxed warning about thyroid C-cell tumors observed in rats; the risk in people is unknown. Do not use with a personal or family history of medullary thyroid carcinoma or MEN 2. Common effects include nausea, vomiting, diarrhea, and constipation. Serious risks include pancreatitis, gallbladder problems, dehydration-related kidney injury, and severe allergic reactions. Discuss pregnancy plans and oral contraceptives with a clinician. Do not combine with another tirzepatide product or GLP-1 medicine. Read the full prescribing information and Medication Guide.
Zepbound prescribing information & Medication GuideQuestions about tirzepatide
Does Zepbound come in a pen or a vial?
Both. Zepbound comes in prefilled pens and in vials used with a separate syringe. Your pharmacist can show you how to use the version on your prescription.
How can I tell if my tirzepatide vial is Zepbound?
Look for the brand name Zepbound on the vial and carton. Tirzepatide is the active ingredient. If your label gives only the ingredient name, ask your pharmacist to confirm which product you received.
How do I book a visit, and what does it cost?
The first weight management visit is $79. Choose Weight management on the consultation page to review the visit details. The clinical practice handles scheduling for your state. If your clinician prescribes tirzepatide, the pharmacy quotes the medication separately. View consultation options