What the research shows
Ten healthy adults took DMAA, caffeine, or both on different days in a blinded crossover experiment. Blood pressure rose after DMAA and the largest rise occurred with the higher DMAA and caffeine combination. Heart rate changed little. The measurements covered two hours and tell us little about repeated exposure or rare cardiovascular events. Blood pressure and heart rate in the crossover study.
FDA identifies DMAA as an unsafe additive in products marketed as dietary supplements in the United States and advises against using them. FDA’s DMAA ingredient record.
Documented formats
The experiment used oral study material. A multi-ingredient pre-workout introduces additional stimulants that have to be identified separately.
Testing and purity
Look for the specific 1,3-dimethylamylamine identity on the report. Identifying the stimulant requires separation from caffeine and closely related amines.
How to read a batch reportQuestions about DMAA
Does “geranium extract” establish where DMAA came from?
FDA reports that it has found no reliable evidence that plants naturally contain DMAA. Botanical origin would require independent identification and source records.
Why report both pulse and blood pressure?
The study measured them separately. A stable pulse coexisted with higher blood pressure in these participants.